12/13/07

Mesothelioma - Clinical Trials


If you are one of the people diagnosed with mesothelioma each year, clinical trials may offer the best available treatment and the opportunity to receive new, potentially more effective therapy. MesotheliomaHelp.net has provided the following information regarding clinical trials to help you locate resources for new mesothelioma treatments. Please contact the individual treatment centers for more information about participation.

Title: ALIMTA (pemetrexed) Plus Gemcitabine (Gemzar) for Patients with Malignant Pleural or Peritoneal Mesothelioma who have not had previous chemotherapy
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There may be multiple sites in this clinical trial including: Colorado, Florida, Illinois, Maryland, Massachusetts, Michigan, New Mexico, New York, Ohio, Pennsylvania, and Wisconsin.


Title: ONCONASE ® plus doxorubicin vs. doxorubicin for patients with Malignant Pleural or Peritoneal Mesothelioma who have had no more than one prior chemotherapy
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San Diego, CA; Sharp Clinical Oncology Research


Title: Open-Label Study of ALIMTA (pemetrexed) in Combination with Cisplatin for Chemonaive Patients with Malignant Pleural Mesothelioma
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The purpose of this protocol is to extend the clinical experience with ALIMTA plus cisplatin in patients with malignant pleural mesothelioma and to collect additional safety information in this patient population.


Title: Phase II trial of combined resection, intraperitoneal chemotherapy, and whole abdominal radiation for treatment of peritoneal mesothelioma
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Columbia-Presbyterian Medical Center, New York, NY


Title: Phase II trial of perioperative gemcitabine and cisplatin chemotherapy in resected pleural mesothelioma
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Eligibility Requirements:
Histologically confirmed malignant pleural mesothelioma
No prior chemotherapeutic regimens


Title: Trimodal Therapy, Phase II trial of combined resection, intraperitoneal chemotherapy, and whole abdominal radiation in peritoneal mesothelioma
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Columbia University Hospital / Cancer Center at Columbia University: New York, NY


Title: Phase II Study of Neoadjuvant Pemetrexed Disodium and Cisplatin Followed By Extrapleural Pneumonectomy and Radiotherapy in Patients With Stage I, II, or III Pleural Mesothelioma
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Memorial Sloan-Kettering Cancer Center. Study Sites in Boston, MA and New York, NY.

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The following websites provide lists of clinical trials for mesothelioma sufferers:

National Cancer Institute's Clinical Trials Finder

ClinicalTrials.gov: Mesothelioma Trials

CenterWatch: Clinical Trials Listing Service

Eli Lilly Mesothelioma Clinical Trials


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